Over the years, studies conducted regarding multiple sclerosis, specifically regarding the causative factors that derive the condition have proved less effective. Up to date, the cause of multiple sclerosis remains unknown. In addition to this, the development, severity, and particular indicators of the illness in any single individual cannot undergo prediction. Because of this, research on the aspects responsible for multiple sclerosis has focused considerably on the plausible role that nature and nurture may pose with respect to causation. Currently, scientists assume that the illness is prompted by unknown environmental factors in an individual genetically inclined towards response. In this respect, a possible relationship between genes and environmental factors encompassing a person may contribute to the origination of multiple sclerosis. Undeniably, the predisposition towards the nature-nurture approach has elicited informative data regarding the derivation of the disease in question across the scientific community. Accordingly, hereditary factors have been established as responsible for the contraction of multiple sclerosis especially among persons inclined towards the particular disease. Alternately, certain genetic materials may predispose individuals to the risk of contracting multiple sclerosis, especially if a response is initiated towards a particular environmental agent. Furthermore, persons from families with members that suffer from the ailment in question may also be inclined towards it more considerably. On the other hand, other studies illustrate that environmental constructs such as race, conditions such as the latitude, smoke from cigarettes, Vitamin D, and the Epstein-Barr virus, weather and ecological conditions may trigger multiple sclerosis in persons. Even though the cure for the disease remains unknown, predisposition towards the relationship between genes and the environment may prove instrumental in unearthing the causative aspects responsible for multiple sclerosis.

Keywords: multiple sclerosis, nature and nurture, genes, environmental factors, gene-environment interaction

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